Nobel Biocare ventures into synthetic-membrane technology to further expand regenerative portfolio

Nobel Biocare has made a key addition to the creos™ regenerative portfolio, introducing its first synthetic membrane, creos™ syntoprotect. Clinicians now have the choice of synthetic and natural materials, as it joins the existing selection of creos™ xenogain, creos™ xenoprotect, creos™ allo.gain, creos™ allo.protect, creos™ mucogain and wound dressings.    

Nobel Biocare has partnered with the synthetic membrane top quality manufacturing site and launched a line of dense PTFE membranes, expanding its portfolio of regenerative products. The move allowed Nobel Biocare and its family of carefully designed regeneration solutions – creos™ – to take a decisive step towards meeting the ever-diverse needs of dental professionals. 

The creos™ syntoprotect dense PTFE membranes are designed to withstand exposure to the oral cavity for extraction socket management when primary closure is not possible. The line also offers 13 shapes of titanium-reinforced dense PTFE membranes for ridge augmentations and grafting large osseous defects. 

By launching creos™ syntoprotect, Nobel Biocare brought to market a solution that is based on an established technology with more than 25 years of clinical practice. 

“With creos™ syntoprotect we aim to provide our customers with the confidence and peace of mind they are looking for,” said Philip Schulze-Smidt, VP / GM Regenerative Solutions, Business Development & Strategy. “The result is a line of synthetic solutions that promises to bring proven predictability1,2 and efficacy3,4,5 to tissue and bone regeneration, while introducing attractive design features.”

Finally, the 13 titanium-reinforced membrane options are easy to trim and versatile in shaping and positioning.

“Every patient is different: we know it and our customers know it. creos™ syntoprotect marks a turning point for our creos™ line, complementing our barrier membrane offering so we can provide dental professionals with natural and synthetic solutions for different indications, from a source they can trust,” added Philip Schulze-Smidt.

creos™ syntoprotect is available in Europe and the United States, where the line of creos™ regenerative products is conveniently available from the Nobel Biocare online store or through any Nobel Biocare Sales Representative. 
creos™ syntoprotect will become available in additional geographies in the coming months.

For more information on creos™ and the recently launched creos™ syntoprotect, dental professionals can visit or contact their local Sales Representative.

1. Barboza EP, Stutz B, Ferreira VF, Carvalho W. Guided bone regeneration using nonexpanded polytetrafluoroethylene membranes in preparation for dental implant placements - a report of 420 cases. Implant Dent. 2010;19:2-7. 
2. Hoffman O, Bartee BK, Beaumont C, Kasaj A, Deli G, Zafiropoulos GG. Alveolar bone preservation in extraction sockets using non-resorbable dense PTFE membranes: A retrospective non-randomized study. J Periodontol 2008;79:1355-1369. 
3. Fotek PD, Neiva RF, Wang HL. Comparison of dermal matrix and polytetrafluoroethylene membrane for socket bone augmentation: a clinical and histologic study. J Periodontol 2009;80:776-785.
4. Barboza EP, Francisco BS, Ferreira VF. Soft tissue enhancement using non-expanded PTFE membranes without primary closure [abstract]. Presented at the 2008 Research Forum Poster Session. Annual Meeting of the American Academy of Periodontology (AAP) in Seattle, WA, September 6-9, 2008. 
5. Ronda M, Rebaudi A, Torelli L, Stacchi C. Expanded vs. dense polytetrafluoroethylene membranes in vertical ridge augmentation around dental implants: a prospective randomized controlled clinical trial. Clin. Oral Impl. Res. 2014 Jul;25(7):859-66.

Nobel Biocare is a world leader in the field of innovative implant-based dental restorations. The company's portfolio offers solutions from single tooth to fully edentulous indications with dental implant systems (including Nobel Biocare N1™, NobelActive®, NobelParallel™, and the All-on-4® treatment concept), a comprehensive range of high-precision individualized prosthetics and CAD/CAM systems (NobelProcera®), prefabricated prosthetics, and a wide variety of regenerative solutions (creos™). Products are supported by a single digital platform for imaging, diagnostics, and treatment planning (DTX Studio™ suite), and guided and navigated surgery (NobelGuide® and X-Guide®). Nobel Biocare supports its customers through all phases of professional development, offering world-class training and education along with practice support and patient information materials. The company is headquartered in Zurich, Switzerland, and production takes place at sites located in the United States and Sweden. Products and services are available in over 50 countries through subsidiaries and distributors. Nobel Biocare is part the Envista family, one of the largest global dental products companies with more than 30 trusted dental brands. For more information, please visit

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