All-on-4® treatment concept

Life-changing treatment – a new smile in a day.*,1,2

The patient-friendly, scientifically proven, full-arch rehabilitation.3

Transforming people’s lives for 25 years

Stand out as a leading practitioner by offering your patients the only fixed full-arch treatment with 25 years of documented clinical success and over 250,000 patients9 successfully treated.4

The original graftless full-arch solution on four implants

The All-on-4® treatment concept is a cost-efficient, graftless solution that provides patients with a fixed full-arch prosthesis on the day of surgery.*,1,2
Nobel Biocare offers an extensive implant range for graftless treatment – from standard to challenging cases.

All on 4 treatment concept

Full-arch rehabilitation with only four implants

Two straight anterior implants and two posterior implants tilting up to 45° and avoiding the anatomical structures.

Provide your patients with provisional teeth in a day*,1,2

Immediate Function for patients meeting criteria for immediate loading of implants.

One surgery

Graftless procedure for shorter treatment time and reduced costs, compared to conventional full arch treatments.5

Supporting bone and soft tissue health

Studies show stable marginal bone levels and healthy soft tissue both for tilted and axial implants.6,7

Implant choices

Nobel Biocare offers the widest range of implants available for graftless treatment of edentulous and soon-to-be edentulous patients.

95% of patients are satisfied with their new teeth8

Over 250,000 patients treated9

Excellent mean implant survival of 98% with a mean follow-up to 7.5 years9


“The high implant and prosthetic survival rates of the All-on-4® treatment concept make it a safe and predictable surgical protocol from both the clinician's and the patient's point of view. Clinicians should adopt this treatment concept in their daily practice to avoid demanding and time-consuming additional surgeries.“

All on 4 Excellence Center


All-on-4® Centers of Excellence

Helping patients find highly experienced doctors who offer the All-on-4® treatment concept in their area.


Learn from the experts

Watch this online course "The All-on-4® treatment concept" at your convenience. Created to help you implement this concept in your practice, this introductory course is designed for surgeons, restorative dentists, general practitioners and their teams.

Get started with the All-on-4® treatment concept

Is the All-on-4® treatment concept right for your practice? This e-book is intended to assist experienced clinicians make an assessment, with real life cases and expert tips.

Find a course in full-arch rehabilitation

Learn how to provide solutions for treating edentulous and soon-to-be edentulous patients with efficient, graftless options for the maxilla and mandible.


Questions about the All-on-4® treatment concept?

If you would like additional information, more details, or have specific questions about the All-on-4® treatment concept, click the link.

Science First issue about the All-on-4 treatment concept

A new issue of the Science First journal is out. 

Transforming lives with the All-on-4® treatment concept



See Instructions For Use for full prescribing information, including indications, contraindications, warnings and precautions. 

*If patient criteria are met and adequate stability achieved  – all our implants can be loaded with a fixed provisional restoration on the day of surgery. 

  1. Weinstein R, Agliardi E, Fabbro MD, et al. Immediate rehabilitation of the extremely atrophic mandible with fixed full-prosthesis supported by four implants. Clin Implant Dent Relat Res 2012;14(3):434-441.  
    Read on PubMed
  2. Agliardi E, Clericò M, Ciancio P, Massironi D. Immediate loading of full-arch fixed prostheses supported by axial and tilted implants for the treatment of edentulous atrophic mandibles. Quintessence Int 2010;41(4):285-293.  
    Read on PubMed
  3. Babbush CA. Posttreatment quantification of patient experiences with full-arch implant treatment using a modification of the OHIP-14 questionnaire. J Oral Implantol 2012;38(3):251-260.  
    Read on PubMed
  4. Maló P, de Araújo Nobre M, Lopes A, et al. The All-on-4 treatment concept for the rehabilitation of the completely edentulous mandible: A longitudinal study with 10 to 18 years of follow-up. Clin Implant Dent Relat Res 2019; doi: 10.1111/cid.127692019  
    Read on PubMed
  5. Patzelt SB, Bahat O, Reynolds MA, Strub JR. The All-on-Four treatment concept: a systematic review. Clin Implant Dent Relat Res 2014;16(6):836-855.  
    Read on PubMed
  6. Agliardi EL, Pozzi A, Stappert CF, et al. Immediate fixed rehabilitation of the edentulous maxilla: a prospective clinical and radiological study after 3 years of loading. Clin Implant Dent Relat Res 2014;16(2):292-302.  
    Read on PubMed
  7. Balshi TJ, Wolfinger GJ, Slauch RW, Balshi SF. A retrospective analysis of 800 Brånemark System implants following the All-on-Four™ protocol. J Prosthodont 2014;23(2):83-88.  
    Read on PubMed
  8. Babbush CA, Kanawati A, Kotsakis GA, Hinrichs JE. Patient-related and financial outcomes analysis of conventional full-arch rehabilitation versus the All-on-4 concept: a cohort study. Implant Dent 2014;23(2):218-224.  
    Read on PubMed
  9. Nobel Biocare. Data on File.