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Introducing creos regenerative solutions

by: Henrik Opelz

Providing bone regeneration options for a wide variety of indications

With an estimated half of all dental implant cases requiring a regenerative procedure, dental professionals need guided bone and guided tissue regeneration products they can trust. 

Enter Nobel Biocare’s new creos line, an extensive array of regenerative options to cover a wide range of indications.

The creos portfolio includes both allogenic products, which are first being launched in the United States, and a xenogenic option, which is being introduced initially in selected European markets, South Africa and Hong Kong.

Perfectly placed protection that endures

The creos xenoprotect resorbable collagen membrane was the first product-to-market, having impressed clinicians during a case series. It is the lone xenogenic product at the moment, but a larger range is coming soon.

The creos xenoprotect membrane acts as a strong barrier to unwanted cells while simultaneously paving the way for the in-growth of osteogenic cells and blood vessel penetration.

It exhibits exceptional strength thanks to its natural collagen structures—no cross-linking agent is used to reinforce the membrane. By ensuring optimum conditions for tissue integration, the new bone and soft tissue are able to develop effectively for a more predictable outcome.

Clinical case series and early feedback confirm that the handling properties of the membrane are its standout attribute. Easily unfolded and not sticky when moistened, creos xenoprotect can be repositioned without displacing the graft material.

Because it increases less in size when hydrated than competitive products, creos xenoprotect takes out the guesswork when trimming the membrane.

The creos xenoprotect membrane also possesses high mechanical stability and is tear-resistant, meaning it can easily be tacked or sutured to stay in the desired position for facilitating new tissue growth.

This feature is great for improving the treatment outcome and for reducing the number of membranes inadvertently torn during application, saving the clinician time and money.

Similarly biocompatible, reliable and pliable is the creos allo.protect allogenic pericardium membrane. Like creos xenoprotect it is designed for use in guided bone regeneration (GBR) and guided tissue regeneration (GTR) procedures.

The creos allo.protect membrane is also quick to place and easy to handle, while offering protection that endures.

Its impressive stability and strength come from the natural pore structure of the pericardium. Clinician and patient alike can have every confidence in the protection it gives to the bone graft.

Lots to gain

The creos allograft portfolio extends to bone grafting materials. Every case is different, which is why the new range of creos allo.gain particulates is extensive. This broad portfolio offers five choices of particulate type that vary in size and volume.

Depending on indication and personal preference, clinicians can choose from corticocancellous, cancellous, cortical and demineralized cortical bone types, as well as a pre-prepared blend of mineralized and demineralized cortical particulate.

In addition to bone particulates, the creos allo.gain offering includes demineralized bone matrix (dbm) putty. Moldable and with a convenient dispenser, creos allo.gain dbm putty can be shaped for precise adaptation to contained defects. This opens up a host of different options for the clinician placing the graft.

Thanks to a unique processing method, the putty is 100% pure allograft, and does not contain any additional filler material. Nevertheless, the presence of natural growth factors is not left to chance. Each donor lot is verified for bone morphogenetic proteins (BMPs). The creos allo.gain dbm putty resists hydration and maintains the stability and space needed for a trouble-free healing period, increasing the predictability of the final result.

Safety first

Ensuring the safety and quality of tissue grafts is of paramount importance, which is why strict processing procedures are in place for all Nobel Biocare’s new regenerative products. Nobel Biocare sources its creos allograft tissue from a supplier that is accredited by the American Association of Tissue Banks (AATB). Individually processing the tissue from each donor in a sterilized environment prevents cross-contamination.

More than a product

At Nobel Biocare the responsibility that comes with being a provider of allograft products is taken very seriously. The new allograft range is only possible thanks to human donors from across the United States. Their generous gift significantly enhances other people’s lives.

Each precious donation therefore demands respect. That’s why Nobel Biocare was extremely careful in selecting the right tissue bank for the creos allograft portfolio. The company’s chosen partner goes to great lengths to assist the families of donors and provide the support that they require.

The introduction of the creos range emphasizes Nobel Biocare’s long-standing commitment to improving quality of life through innovation.

Like all other Nobel Biocare products, these new regenerative solutions will make a positive difference—both to the results dental professionals can achieve and to their patients’ quality of life. 

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To learn more about Nobel Biocare's regenerative solutions, please click here.

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