To date more than 3000 NobelActive implants have been clinically documented in over 1300 patients, including in published studies with three-year follow-up data.1,2 The results have been remarkable, not least because NobelActive’s unique design has been recognized as supporting implant placement even in compromised situations. Its variable thread design “cuts” soft bone as it is placed, enabling implant placement with a narrower osteotomy.
NobelActive has demonstrated limited bone loss during the initial remodeling period2 and stable or even improving bone levels within the first two years. With its conical connection design, NobelActive has been shown to offer statistically better radiological marginal bone crestal levels and less marginal bone loss in comparison with a control implant, both from implant placement to loading and from baseline to one year of function. This has been confirmed in two studies with different control implants.4,5
Studies conducted using NobelActive have proven that the same clinical and esthetic results can be achieved with Immediate Function as with delayed loading, including in demanding conditions such as extraction sites. Recent studies have shown high implant survival rates with Immediate Function.1,2,6 When using Immediate Function NobelActive has also demonstrated statistically significant papilla improvement over three years follow-up.1,2
When surveyed, patients reported statistically significant increases in function, esthetics, sense, speech and self-esteem over three years of follow-up after having NobelActive implants placed with Immediate Function in extraction sites of failing teeth.1
When it comes to edentulous patients, NobelActive is also a safe and effective option. Performing as well in the maxilla as it does in the mandible8, and effective even in severely atrophic jaws, studies have shown predictable implant performance with the All-on-4® treatment concept.6,7,8 NobelActive has even demonstrated its efficacy in patients with osteoporosis.9
1 Kolinski ML, Cherry JE, McAllister BS, Parrish KD, Pumphrey DW, Schroering RL. Evaluation of a variable-thread tapered implant in extraction sites with immediate temporization: A 3-year multi-center clinical study. J Periodontol. 2013 Jun 27. [Epub ahead of print]
2 Arnhart C, Kielbassa AM, Martinez-de Fuentes R, Goldstein M, Jackowski J, Lorenzoni M, Maiorana C, Mericske-Stern R, Pozzi A, Rompen E, Sanz M, Strub JR. Comparison of variable-thread tapered implant designs to a standard tapered implant design after immediate loading. A 3-year multicentre randomised controlled trial. Eur J Oral Implantol. 2012 Summer;5(2):123-36.
3 McAllister BS, Cherry JE, Kolinski ML, Parrish KD, Pumphrey DW, Schroering RL. Two-year evaluation of a variable-thread tapered implant in extraction sites with immediate temporization: a multicenter clinical trial. Int J Oral Maxillofac Implants. 2012 May-Jun;27(3):611-8.
4 Pozzi A, Agliardi E, Tallarico M, Barlattani A. Clinical and Radiological Outcomes of Two Implants with Different Prosthetic Interfaces and Neck Configurations: Randomized, Controlled, Split-Mouth Clinical Trial. Clin Implant Dent Relat Res. 2012 Jun 1. doi: 10.1111/j.1708-8208.2012.00465.x. [Epub ahead of print]
5 Gultekin BA, Gultekin P, Leblebicioglu B, Basegmez C, Yalcin S. Clinical evaluation of marginal bone loss and stability in two types of submerged dental implants. Int J Oral Maxillofac Implants. 2013 May-Jun;28(3):815-23. doi: 10.11607/jomi.3087.
6 Galindo DF, Butura CC. Immediately loaded mandibular fixed implant prostheses using the all-on-four protocol: a report of 183 consecutively treated patients with 1 year of function in definitive prostheses. Int J Oral Maxillofac Implants. 2012 May-Jun;27(3):628-33.
7 Babbush CA, Brokloff J. A single-center retrospective analysis of 1001 consecutively placed NobelActive implants. Implant Dent. 2012 Feb;21(1):28-35. doi: 10.1097/ID.0b013e3182344fce.
8 Babbush CA, Kanawati A, Brokloff J. A New Approach to the All-on-Four Treatment Concept Using Narrow Platform NobelActive Implants. J Oral Implantol. 2013 Feb 11. [Epub ahead of print]
9 Aspriello SD, Rasicci P, Ciolino F, Zizzi A, Rubini C. Procaccini M, Piemontese M. Immediate loading of NobelActive implants in postmenopausal osteoporotic women: 2-years follow up study. 20th Annual Scientific Meeting of the European Association for Osseointegration (Abstract #222) (2011), Abstracts. Clinical Oral Implants Research, 22: 882–1104. doi: 10.1111/j.1600-0501.2011.02271