A comprehensive range of xenogenic bone substitutes
The natural framework for bone formation
The creos xenogain portfolio comprises an extensive range of non-sintered xenogenic bone substitutes for guided bone regeneration (GBR) and guided tissue regeneration (GTR) procedures.
The comprehensive range includes:
Why creos xenogain?
Treat your patients with confidence
creos xenogain is biocompatible.3,4,5,6 Unique processing methods remove the bovine proteins and lipids.1,2 With a calcium phosphate ratio that reflects the composition in human bone and a low crystalline structure, creos xenogain is accepted by the body as a suitable framework for bone formation.2,7,8
The scaffold for successful regeneration
creos xenogain is characterized by a preserved natural bone matrix with micro- and interconnected macropore structures.1,2 It offers a suitable environment for new bone formation.2,3,4 creos xenogain promotes rapid hydration (capable to absorb 1.75x its weight of water mass in a few seconds).1
A solid foundation for implant treatment
creos xenogain acts as a slowly resorbing scaffold and maintains space for bone regeneration.4 The graft integrates with the newly formed bone, building a basis for successful implant placement.
Dr. Bastian Wessing, Germany
“What impressed me about this product was the variety of sizes and dosage forms, each offering very good handling properties.”
Univ.-Prof. DDr. Werner Zechner, Austria
"After using the non-sintered creos xenogain bone substitute, I appreciated its handling properties and I see its high hydrophilicity as a biological advantage in peri-implant defect regeneration and sinus grafting"
1 Data on file NIBEC
2 Data on file Nobel Biocare Material properties of CXG / biomaterials
3 Park H-N, et al. A study on the safety and efficacy of bovine bone-derived bone graft material(OCS-B). J Korean Acad Periodontol. 2005 Jun;35(2):335–43
4 Park J-B, et al. Maxillary sinus floor augmentation using deproteinized bovine bone-derived bone graft material(OCS-B). Clinical and histologic findings in human. The Journal of the Korean Dental Association. 2007;45(8):491–99
5 Shin S-Y, et al. Long-term results of new deproteinized bovine bone material in a maxillary sinus graft procedure. J Periodontal Implant Sci. 2014;44:259–64
6 Data on file NIBEC Biocompatibility tests: OCS-B and OCS-B Collagen
7 Kyriazis V, Tzaphlidou M. Skeletal Calcium/Phosphorus Ratio Measuring Techniques and Results. I. Microscopy and Microtomography. The Scientific World Journal. 2004;4:1027–34
8 Data on file NIBEC Atomic emission spectrometry analysis
9 Data on file NIBEC Porosity Analysis (BET measurement)