creos xenogain

A comprehensive range of xenogenic bone substitutes

The natural framework for bone formation

creos xenogain comprehensive range

The creos xenogain portfolio comprises an extensive range of non-sintered xenogenic bone substitutes for guided bone regeneration (GBR) and guided tissue regeneration (GTR) procedures. 

The comprehensive range includes:

  • creos xenogain – deproteinized bovine bone mineral matrix with preserved micro- and macrostructures.1,2
  • creos xenogain collagen – a composite of creos xenogain and 10% porcine collagen type 1.

Why creos xenogain?

Easy handling

For quick and easy application of the graft, creos xenogain bone substitutes are delivered sterile and come either in a vial, in a syringe or in a bowl ready for mixing. Two granule sizes and up to four volume options offer a wide variety of alternatives.

Treat your patients with confidence

creos xenogain is biocompatible.3,4,5,6 Unique processing methods remove the bovine proteins and lipids.1,2 With a calcium phosphate ratio that reflects the composition in human bone and a low crystalline structure, creos xenogain is accepted by the body as a suitable framework for bone formation.2,7,8

The scaffold for successful regeneration

creos xenogain is characterized by a preserved natural bone matrix with micro- and interconnected macropore structures.1,2 It offers a suitable environment for new bone formation.2,3,4 creos xenogain promotes rapid hydration (capable to absorb 1.75x its weight of water mass in a few seconds).1

A solid foundation for implant treatment

creos xenogain acts as a slowly resorbing scaffold and maintains space for bone regeneration.4 The graft integrates with the newly formed bone, building a basis for successful implant placement.

creos xenogain collagen

A composite of creos xenogain and 10% porcine collagen type 1 for easy graft application e.g. in extraction sockets, that is available as a block or a syringe.

creos xenoprotect

Once the bone substitute is applied, the resorbable creos xenoprotect membrane can be used to hold it in place and act as a barrier to soft tissue ingrowth. 

Learn more

Testimonials

Dr. Bastian Wessing, Germany

Dr. Bastian Wessing, Germany

“What impressed me about this product was the variety of sizes and dosage forms, each offering very good handling properties.”

Univ.-Prof. DDr. Werner Zechner, Austria

Univ.-Prof. DDr. Werner Zechner, Austria

"After using the non-sintered creos xenogain bone substitute, I appreciated its handling properties and I see its high hydrophilicity as a biological advantage in peri-implant defect regeneration and sinus grafting"

Literature

 

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References

1 Data on file NIBEC

Data on file Nobel Biocare Material properties of CXG / biomaterials

Park H-N, et al. A study on the safety and efficacy of bovine bone-derived bone graft material(OCS-B). J Korean Acad Periodontol. 2005 Jun;35(2):335–43

4 Park J-B, et al. Maxillary sinus floor augmentation using deproteinized bovine bone-derived bone graft material(OCS-B). Clinical and histologic findings in human. The Journal of the Korean Dental Association. 2007;45(8):491–99

5 Shin S-Y, et al. Long-term results of new deproteinized bovine bone material in a maxillary sinus graft procedure. J Periodontal Implant Sci. 2014;44:259–64

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6 Data on file NIBEC Biocompatibility tests: OCS-B and OCS-B Collagen

7 Kyriazis V, Tzaphlidou M. Skeletal Calcium/Phosphorus Ratio Measuring Techniques and Results. I. Microscopy and Microtomography. The Scientific World Journal. 2004;4:1027–34

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8 Data on file NIBEC Atomic emission spectrometry analysis

Data on file NIBEC Porosity Analysis (BET measurement)