NobelScience

NobelScience

The science behind the single-tooth restoration

Replacing a single tooth is complex. Explore evidence and expert insights on biology‑driven planning, implant positioning, and restorative precision

Own the zone science first journal

The latest issue of the Science First journal is out

Esthetic edge: The science behind owning the zone

Science in motion

Hear directly from clinicians as they explain the "why" behind predictable single-tooth protocols – what to prioritize, what to avoid, and how to plan for long-term tissue stability.

Clinical case stories 

Take a read through our favorite clinical stories to see how experts approach complex cases – from missing lateral incisors to trauma rehabilitation. These real-world examples showcase advanced planning, surgical precision, and esthetic outcomes that inspire confidence and learning.

Ann Wei

Single tooth replacement in a thin biotype: A staged implant and digital prosthetic approach

Dr. Ann Wei presents a clinical case of single-tooth replacement in the esthetic zone of a patient with a thin gingival biotype, where maintaining soft tissue stability is particularly challenging

Review the clinical approach >

Dr. Edith Groenendijk

“There is no anterior case in which I don’t consider FIIPP first.”

Dr. Edith Groenendijk presents FIIPP protocol enabling flapless immediate implant placement with N1 system, preserving soft tissue, optimizing positioning, and delivering predictable esthetic outcomes.

Review the clinical approach >

Dr. Hagan

See how NobelActive 3.0 solves narrow space challenges

Dr. Mark Hagan shares a detailed clinical case on restoring congenitally missing lateral incisors with implant therapy designed for long-term stability and esthetics.

View the case report >

Dr. Tartsch

A metal-free solution for restoring natural esthetics

With Dr. Jens Tartsch, explore metal‑free restorative dentistry that combines natural esthetics, biocompatibility, and strength, demonstrated through a documented clinical case with precision and predictable, patient‑centered outcomes.

Explore the case >

Dr. Todescan

A stepwise approach to esthetic zone reconstruction: clinical case insights

Discover how Prof. Francisco Todescan and his team approach esthetic zone reconstruction, where thoughtful implant planning and refined soft‑tissue management deliver predictable, natural‑looking anterior outcomes.

See the clinical outcome >

Dr. Lundgre

Rehabilitation of anterior maxilla with limited spaces after traumatic injury

Join Prof. Stefan Lundgren as he shares advanced strategies for rehabilitating the anterior maxilla after trauma—combining smart implant planning, esthetic control, and predictable results in limited spaces.

Review the clinical approach >

Editor's pick

Peer tips 

Learn directly from experienced clinicians as they share their evidence-based approaches to single-tooth rehabilitation, from straightforward cases to the most challenging scenarios. Each insight is backed by their research and published studies, highlighting the importance of scientific rigor, precision, and premium materials in achieving predictable outcomes.

  • Membrane exposure: clinical view

    A multicenter study on creos™ biomaterials for GBR in large horizontal defects revealed strong bone gain and high patient satisfaction. Interviews with Drs. Lorenz and Magic emphasized the importance of managing dehiscence and membrane exposure with minimal intervention, highlighting the value of PROMs and the handling properties of creos™ xenoprotect.

    Dr. Lorenz and Dr. Magic
    Explore this multi-center clinical study
  • Procera™ restorations in single tooth indication: low complication rate 

    A multicenter study of 463 CAD/CAM NobelProcera® individualized abutments shows a 98.1% prosthetic survival rate and just 1.5% technical complications over 6.4 years. With high patient and clinician satisfaction, these fully screw-retained solutions demonstrate long-term reliability and esthetic success.

    Explore this clinical study
  • What 15 years taught us: Evidence based planning

    A 15-year retrospective study conducted by Drs. Jan Kowar, Henrik Lund, and Victoria Franke Stenport evaluated 129 TiUnite surface implants used in single-tooth restorations. The results showed a high survival rate and minimal complications, with stable bone levels and low incidence of peri-implantitis. The study underscores the importance of careful planning, precise placement, and patient compliance for long-term implant success.

    Explore the 15-year study on single-tooth implant success
  • “We can’t plan a smile without understanding how it fits into the patient’s facial dynamics."

    Implant planning by Dr. Francesco Mintrone integrates digital planning and socket shield technique to enhance esthetic outcomes, precision, and long term tissue stability.

    Francesco Mintrone
    Read the full interview
  • Immediate implants in extraction socket

    Dr. Iñaki Gamborena presents clinical insights on immediate implant placement in fresh extraction sockets, emphasizing the importance of soft tissue management and prosthetic planning. His approach highlights how careful timing and anatomical considerations can lead to predictable esthetic outcomes and long-term success. The article showcases his technique and rationale for achieving optimal results in challenging cases

    Dr. Gamborena masterclass
    Learn Dr. Gamborena’s approach to immediate implant placement
  • “Progress in implants with no change in protocol appeals a lot to my trainees”

    Dr. Bobby Birdi highlights how Nobel Biocare’s implant systems—particularly NobelActive—enable clinical progress without requiring changes to established protocols. This consistency appeals to trainees and clinicians alike, offering predictable outcomes and streamlined workflows. The article emphasizes how maintaining protocol stability can support both learning and long-term success in implantology.

    Wide platform (WP) NobelActive™ implant
    Explore Dr. Birdi's views on these surface

Science Hub (ready to download)

Access print-ready summaries of key clinical studies focused on single-tooth rehabilitation – whether in the anterior or posterior region, maxilla or mandible. These resources highlight outcomes achieved with scientifically proven protocols and premium solutions. Explore white papers that bring together multiple studies to tell a complete story of clinical success, esthetic excellence, and long-term reliability.

White papers and newsletters

N1 White paper

Nobel Biocare N1™ implant system: Precision engineering for clinical predictability

Successful clinical outcomes with TiUltra™ surface: Emerging data

NobelPearl™: metal-free two-piece implant solution

creos™ xenoprotect: strong native collagen membrane

creos™ xenoform: an all-cancellous bone graft

Clinical studies

Robust papilla regeneration and marginal bone gain with TiUltra™ and Xeal™ surfaces: 2-year results

Significantly increased soft tissue thickness around NobelActive® TiUltra™ and On1™ Base Xeal™ after 1 year

15 years of clinical success: single-tooth restoration with anodized implants

Nobel Biocare N1™ concept: one versatile and simplified solution for clinical success in all indications

Nobel Biocare N1™ concept: biologically friendly innovation reduces cell death

NobelParallel™ CC implants support success, even in challenging situations

Five years of esthetic excellence with NobelReplace® CC and NobelProcera® in the anterior maxilla

Excellent prosthetic survival and low complication rate with 463 CAD/CAM NobelProcera® abutments

Excellent long-term outcomes with NobelActive and immediate protocols in esthetic zone

Successful regeneration of large horizontal defect in the posterior mandible using creos™ biomaterials

Significantly increased soft tissue thickness around NobelActive® TiUltra™ and On1™ Base Xeal™ after 1 year

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