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NobelScience

The science behind preventing complications

Explore the science behind our innovations and solutions to prevent and manage complication in real clinical setting, and see how evidence drives excellence.

Why TiUltra™ surfaces? Because you deserve real science

Explore the predictability of TiUltra™ surface, the role of premium manufacturing on surface cleanliness, and innovations in handling complication.

Tiultra real science

Science in motion

Every solution we bring forward is grounded in rigorous research, designed to deliver predictable outcomes and prevent complications. Explore the science behind our innovations and solutions to prevent and manage complications in real clinical settings, and see how evidence drives excellence.

Clinical case stories 

Explore step-by-step clinical cases grounded in science, focusing on prevention and management of complications. Learn how evidence-based protocols, clinician expertise, and premium, scientifically validated solutions work together to control variables, reduce risk, and support predictable outcomes in everyday practice with practical insights for clinicians globally.

Inaki Gamborena

Managing a complex anterior mandibular defect: a step‑by‑step case report

Management of complex anterior mandibular defects: early diagnosis, infection control, and tissue preservation enable predictable, esthetic, long-term implant outcomes.

Explore the case >

Istvan Urban

Soft tissue-centered vertical ridge augmentation in a complex maxillary case

Urban’s biologically driven approach with creos biomaterials prioritizes tissue preservation, reducing complications in demanding cases and enabling stable regeneration and predictable long-term outcomes.

View the case report >

Enrico Agliardi

“The key to success is adhering to surgical and prosthetic protocols.”

All-on-4® treatment concept enables graftless full-arch rehabilitation, optimizing residual bone, implant positioning, N1 system performance, Xeal surface integration, and long-term predictability.

See the clinical outcome >

Editor's pick

Peer tips 

Hear from experienced clinicians as they share evidence-based approaches to preventing and managing complications, supported by premium, scientifically validated materials and innovative solutions. Grounded in clinical research and real-world practice, these insights highlight how precision, advanced technologies, and rigorous protocols contribute to predictable, long-term outcomes and patient safety.

  • Excellent prosthetic survival and a low rate of complications with Procera individualized abutments

    Procera restorations in single tooth indications demonstrate low complication rates, with CAD CAM NobelProcera abutments delivering high survival, prosthetic reliability, and long term esthetic success.

    procera-restorations
    Read more in this interview
  • Impact of dehiscence and membrane exposure on patient satisfaction

    Impact of dehiscence in guided bone regeneration, GBR, horizontal defects, bone gain, patient outcomes, exposure, management.

    Dr. Lorenz and Dr. Magic
    Explore the interview
  • This technique is less invasive and has a shorter healing time

    Immediate implant placement in posterior maxilla with NobelActive and creos biomaterials, optimizing positioning, sinus lift approach, healing time, and predictability

    Prof. Daniele De Santis
    Explore the interview
  • How do we test fatigue, screw loosening, primary stability and more?

    Biomechanics-driven testing validates N1 implant system performance, fatigue strength, connection sealing, and insertion dynamics to ensure safety reliability and predictability.

    Explore the interview
  • Beyond osseointegration: the long-term biological vision in implant prosthodontics

    Dr. Giacomo Fabbri from Italy outlines biologically driven implant position, Xeal surface technology, emergence profile design, and soft tissue stability for predictable long-term outcomes.

    Read the full interview

Science Hub (ready to download)

Discover concise, print‑ready resources highlighting strategies to prevent complications through thorough planning and the use of scientifically tested solutions and materials. These insights demonstrate how evidence‑based protocols, validated workflows, and high‑quality materials support predictable outcomes, risk reduction, and long‑term clinical reliability.

White papers and newsletters

Science Newsletter Compromised patients.pdf

Implant care in medically compromised patients

creos™ xenoprotect: strong native collagen membrane

TiUltra™ surface eliminates the risk of contamination from sand-blasting particles

Precision engineering for clinical predictability

Clinical studies

Large‑scale real‑world evidence: TiUltra™ surface implants in 1000 consecutive patients

One versatile solution for clinical success 

creos syntogain Successful ridge preservation with novel biomimetic bone substitute

Successful regeneration of large horizontal defect in the posterior mandible using creos biomaterials

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