Dr. France Lambert is a Professor in Dental Biomaterials and Head of Clinic in the Department of Periodontology and Oral Surgery at the University of Liège, Belgium. She lectures internationally on her scope of research. In this lecture, she discusses what you should consider when choosing xenogeneic materials for bone regeneration; defect assessment for your clinical strategy; and new research developments in this field.
After providing a brief overview of the principles of GBR, Dr. Lambert considers what makes a xenogeneic material ideal for the treatment of bone defects. She explains that a material should be:
1) biocompatible to avoid foreign body reactions;
2) able to maintain volume over time;
3) osteoconductive for high bone-to-material contact and integration with new bone; and
4) able to enhance bone regeneration to speed up the healing process.
Moving on to defect assessment and clinical strategy, she explains how different indications can have different osteogenic potential. This presents various levels of complexity to the treatment and the possibility to successfully complete implant placement.
Dr. Lambert shows that the osteogenic potential can be related to the number of intact bone walls available at the defect site. Favorable defects, such as an extraction socket with five intact bone walls, have very good osteogenic potential, while vertical bone defects can have very poor osteogenic potential – and are therefore very challenging from the treatment perspective.
Finally, in this presentation at EAO 2018, Dr. Lambert showcases interim preclinical results of a new biomaterial, currently in the experimental phase, that meets the criteria mentioned above, including the possibility to encourage faster bone regeneration compared to a material currently considered a ‘gold standard’.