Nobel Biocare Symposium 2012 - Gothenburg

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P-I Brånemark celebrates the dual anniversaries of osseointegration with Nobel Biocare

Highlights: P-I Brånemark celebrates the dual anniversaries of osseointegration with Nobel BiocareProfessor Per-Ingvar Brånemark made a surprise entrance on March 22 at the first Nobel Biocare scientific symposium of 2012 in Gothenburg, Sweden. The grandfather of implantology joined a long list of his fellow dental implant pioneers to celebrate the dual anniversaries of osseointegration – 60 years since the discovery and 30 years since international acceptance. While his dramatic entry to the symposium was largely unexpected, his presence was warmly welcomed, as the celebration taking place wouldn’t have been the same without him.

Sixty years have now passed since Professor Brånemark’s remarkable discovery that titanium could integrate with bone. He called it “osseointegration” and it changed dentistry forever, improving the lives of millions of people around the world in the years to follow. His arrival at the Gothenburg symposium prompted a standing ovation, but for Brånemark and his supporters it was only an encore call compared to the one they received at the Toronto conference in 1982 after a 30-year fight for acceptance.

The programs of all six Nobel Biocare Symposia 2012 taking place in Sweden, Canada, and also France, Ukraine, Germany and Italy will celebrate the origins and evolution of osseointegration as a practical and trusted treatment modality over the last six decades. Beginning the series in Gothenburg, Chairman of the Scientific Committee, Professor Ulf Lekholm, reminded participants of how far Professor Brånemark, Nobel Biocare and their band of supporters have brought dental innovations based on the principles of osseointegration since those days of breakthrough 60 and 30 years ago.

Professor Lekholm explained that the fight for acceptance began in 1952 when Brånemark first discovered the principles of osseointegration during an experiment where a small titanium-encased microscope lens was placed in a rabbit fibula to study bone regeneration and microcirculation in vivo. Attempts to remove the apparatus proved futile as the titanium had attached to the bone. Realizing the potential of his findings, Brånemark turned his efforts toward dentistry and by 1965 the first patient, Gösta Larsson, had received dental implants.

Bofors, a corporate antecedent to Nobelpharma and Nobel Biocare, produced Brånemark’s early implants. The rest is well-documented scientific history, with over 1200 published osseointegration-based studies and 110 PhD theses presented to date. However, the story of acceptance is a little longer, 30 years to be exact. It turns out it was much harder for minds to accept a new concept than it was for bone to integrate with titanium.

Rebels with a cause
Being on the crest of a growing wave of medical and surgical breakthrough wasn’t as smooth a ride as you would have expected. When Professor Ragnar Adell, who was a research associate in Professor Brånemark’s department from 1967-1974, took the stage in Gothenburg he explained that between the 1950s and 1970s the only outcomes on record for placing metal in bone were not favorable. It had been widely thought and accepted that any metal object placed in bone would not integrate but instead develop a fibrous tissue between the appliance and bone. This fibrous tissue lacked stability and was prone to bacterial infection. Naturally, it was difficult to convince the world that titanium was different, possessing unique properties that are still not fully understood, which allow it to integrate with bone.

Professor Brånemark and his team began facing a hostile environment of disbelief in 1969 in Landskrona at the Southern Swedish Dental Association with comments like, “You are a humbug sir – not even a dentist!” According to Professor Ragnar Adell, the harsh reactions to Brånemark’s findings continued into 1975 where the group was rejected by almost the entire Swedish scientific community. Professor Adell reminisced about a stern finger being waved in his face followed by the dismal suggestion, “You should be expelled!”

It wasn’t long, however, before the tide began to turn. Within a few months of the criticism in Sweden, the health insurance system requested that the Swedish National Health and Welfare Board do a study on the subject of osseointegration. Twenty randomly selected patients were subsequently examined along with the 10 years of meticulously recorded follow-up data produced by Brånemark and his team. The results of the study were indisputable and finally led to Swedish approval. This was the beginning of the long-term credibility that osseointegration enjoys today both in dentistry and beyond according to Professor Adell. “It is an extremely well-documented biological principle for anchorage anywhere in the human skeleton.

A victorious revolution
The battle in Sweden was won, but the war was far from over. Victory in Sweden, and Europe for that matter, was not enough, osseointegration needed to be accepted globally. Around the time of Swedish acceptance, Professor George Zarb from Toronto, Canada read Professor Brånemark’s 10-year follow-up data and also saw the potential of this new development in dental implants. In 1977 he visited Professor Brånemark in Sweden and studied osseointegration for one year. He started the “Republication Study of Osseointegration” in Toronto and published the results in 1979, thus becoming the first researcher outside of Sweden to replicate and verify the results of the Brånemark team.

In May of 1982 Professor Zarb played a pivotal role in furthering the spread of osseointegration. He organized the landmark “Toronto Osseointegration Conference in Clinical Dentistry” which introduced osseointegration to North America, initiating international acceptance. The conference brought the breakthrough treatment modality to the swift attention of academic communities and thus the general public.

“Professor Brånemark bridged the gap from mechanics to biology,” explained Professor Zarb, who also made the trip to speak at the Gothenburg symposium. He referred to the time period before Brånemark as “B.B.” Professor Zarb who will lead the Nobel Biocare symposium in Toronto as the Chairman of the Scientific Committee, went on to say that before Brånemark there were so many patients who had succumbed to scientific failure but now with osseointegration there is a versatile application for the reduction of bone loss that can truly enrich a patient’s life.

When asked about his reaction after osseointegration was finally accepted internationally, Professor Zarb explained the feeling in one word, “Triumphant!” He further explained that it wasn’t just a victory for the supporters but a victory for dentistry which enriched the entire community. “It was a giant leap of science ... we’ve come a long way.”Highlights: Scientific symposia unlike any other

Scientific symposia unlike any other
An estimated 1000 attendees descended upon the hometown of osseointegration – Brånemark’s Gothenburg – from March 21-23 to celebrate the two anniversaries of osseointegration. The Nobel Biocare Symposia 2012 continue on the road from Sweden to Toronto, with stops along the way in France, Ukraine, Germany and Italy. From all over the world, many more participants are expected to make the pilgrimage to these symposia during the current year. As they do so they will be paying tribute to the discovery that astonished the dental community and sparked new treatment opportunities in such disparate fields as dentistry and orthopedics.


Wednesday, March 21, 2012

15:00-22:00 Registration period
Registration period
19:00 Welcome Reception at Clarion Hotel Post


Thursday, March 22, 2012

07:00-09:00 Registration period


09:00-09:20 Opening ceremony & welcome remarks

Opening ceremony and welcome remarks
Magnus Persson and Richard Laube

09:00-09:20 The Osseointegration Story – a 60-year perspective

The Osseointegration Story – a 60-year perspective
Introductory remarks and a video presentation
Ulf Lekholm

09:50-10:20 Break
10:20-12:00 The Osseointegration Story – in light of the Toronto meeting

The Osseointegration Story – in light of the Toronto meeting
Ulf Lekholm

Providing predictable retention – a professional life-time perspective
Ragnar Adell

Implantomania: Prosthodontics at a Crossroad
George Zarb

12:00-13:00 Lunch


13:00-15:00 Well documented standards in implant surgery

Well documented standards in implant surgery
Christer Dahlin

Variations in surgical techniques due to patient prerequisites
Bertil Friberg

Long-term follow-up of the TiUnite surface
Pär-Olov Östman

Peri-implantitis – diagnostics and treatment possibilities
Stefan Renvert


15:00-15:30 Break
15:30-17:45 Current surgical challenges

Current surgical challenges
Stefan Lundgren

Additional surgical techniques for optimized treatment result
Massimo Simion

Implant surgery in advanced clinical situations
Thomas Kofoed


17:45-18:00 Closing remarks of the first day
19:30 Anniversary Party

Friday, March 23, 2012

08:00-09:45 Clinical considerations in treatment planning

Clinical considerations in treatment planning
Margareta Molin-Thorén

Various prosthetic alternatives in implant treatment
Torsten Jemt

Team-work in prosthetic treatment planning
Nicole Winitsky & Åsa Sjöholm


09:45-10:15 Break
10:15-12:15 Esthetic challenges in implant dentistry

Esthetic challenges in implant dentistry
Klaus Gotfredsen

Systems for evaluation of the esthetic outcome
Rudolf Fürhauser

Clinical performance to achieve good esthetics
Eric Van Dooren


12:15-13:15 Lunch
13:15-14:45 Digital dentistry for optimized patient outcome

Digital dentistry for optimized patient outcome
Kjell Størksen

Digital solutions for planning and treatment aid
Eirik Salvesen

Aspects on digitally guided implant surgery
Stefan Lundgren


14:45-15:15 Break
15:15-16:45 Possible future developments in implant dentistry - something to learn from the history

Possible future developments in implant dentistry - something to learn from the history
Ann Wennerberg

Nanotechnology for implant surface optimization
Ryo Jimbo

Surface properties and microbial biofilms
Julia Davies

Additional Future Considerations
George Zarb Discussions


16:45-17:00 Closing remarks of the meeting

Closing remarks of the meeting
Magnus Persson

Parallel Program, Thursday, 13:00 – 17:00

Scientific Committee

Scientific Committee Chairman

Ulf LekholmDr. Ulf Lekholm received his dental degree at Lund University, Dental Faculty, in Malmö in 1968. He became Doctor of Odontology in 1976 and specialist in oral maxillofacial surgery in 1977 at the Dental Faculty of Gothenburg University. He was appointed the first chairman of the Brånemark Clinic, Gothenburg (1985–2000), and he was appointed professor in oral implant surgery at the University of Gothenburg in 1988. At present he is professor emeritus.


Scientific Committee members

  • Dr. Christer Dahlin, Sweden

  • Dr. Margareta Molin Thorén, Sweden

  • Dr. Kjell Størksen, Norway

  • Dr. Klaus Gotfredsen, Denmark

  • Dr. Ann Wennerberg, Sweden

  • MSc. Camilla Billström, Sweden


Nobel Biocare Symposia 2012 - Gothenburg Speakers

Dr. Ragnar Adell, Sweden

Dr Ragnar Adell received his BDS/DDS degree from the University of Lund 1964. He was a research associate at Professor P-I Brånemark´s department 1967 – 1974 resulting in a PhD-degree 1974. He was appointed associate professor 1975 and became a specialist in Oral and Maxillofacial Surgery 1980. He was a visiting professor with the University of Iowa 1987 – 1988. In 1989 he was appointed head and specialty education program director at the Department of Oral and Maxillofacial Surgery, Örebro University Hospital. He was acting head of the Centre for Head and Neck Oncology at the same hospital 2006 – 2007. Dr Adell has been president for the Swedish Association of Oral and Maxillofacial Surgery. He (partly) retired 2008.

Dr. Christer Dahlin, Sweden

Dr. Christer Dahlin associate professor, head dentist, ÖNH/ Jaw Surgery Clinic NU-medical treatment. University lecturer within Regimented Tissue Regenera¬tion at the department of Biomaterial, University of Gothenburg. Dr Dahlin be¬came authorized dentist i 1985 and specialist in Jaw Surgery in 1998. Defended his thesis about Osteopromotion in 1993. Became unremunerated associate professor at University of Gothenburg in 1997 within Experimental Jaw Surgery. Is Courtesy Professor at the University of Florida, Gainesville, USA. A member of the editorial board in several international scientifical journals. Main research orientation is tissue engineering and craniofacial bone reconstruction. Consider-ed one of the pioneers behind the principle of Guided Bone Regeneration.

Dr. Julia Davis, United Kingdom/Sweden

Julia Davies gained her PhD in Medical Physiology from The University of London, UK and is currently Professor of Oral Biology at the Faculty of Odontology, Malmö University in Sweden. Her primary research interest is in the development of microbial biofilms on oral surfaces, including dental implants, with particular focus upon the influence of the surface in this process.

Dr. Bertil Friberg, Sweden

Dr Bertil Friberg received the DDS degree in 1975. Specialist in maxillofacial surgery. Joined the Brånemark Clinic from its start in 1986. Became a Master of Dental Science in 1994 and Doctor of Odontology in 1999. Associate professor and Co-chairman at the Brånemark Clinic. Performed ~1,000 national and international presentations of the Brånemark System and published >50 scientific papers. Appointed visiting professor at Siena University, Italy, in 2004

Dr. Rudolf Fürhauser, Austria

Rudolf Fürhauser, MD, DMD 1977-1983: Study of Medicine, Medical Faculty, University of Vienna, MD 1983-1987: General practitioner, 1987-1989: Study of Dentistry at the Dental School of Vienna, DMD, 1990-2010: Assistant Professor - Prosthodontic Department of Dental School of Vienna since 2004, Member of the Academy of Oral Implantology since 2011, Medical Director of the Academy of Oral Implantology. Main topics: implant prosthetics, aesthetics, biomechanics, partial denture design.

Dr. Klaus Gotfredsen, Denmark

Prof. Klaus Gotfredsen, Dept. of Oral Rehabilitation at Faculty of Health Sciences, University of Copenhagen graduated in 1984 from the School of Dentistry, University of Aarhus. He received a Danish Ph.D. degree in 1990 from University of Copenhagen and a Swedish Ph.D. degree in 2001 from Dept. of Periodontology, Faculty of Odontology, Göteborg University. Dr. Gotfredsen has published more than 90 scientific papers in the fields of Implant and Prosthetic Dentistry. He serves as reviewer for a number of clinical and scientific journals and has lectured extensively in the field of Implant Dentistry.

Dr. Torsten Jemt, Sweden

Prof. Torsten Jemt was a co-worker to Prof. P-I Brånemark, where he was responsible for development of the first single implant abutments. At Sahlgrenska Academy, Göteborg University, he became Associate Professor (1986) and later served as Professor, Department of Prosthetics and dental materials. He co-founded the Brånemark Clinic and has served as its Chair since 2000. Serving on several editorial boards, he is extensively published and an internationally renowned speaker.

Dr. Ryo Jimbo, Japan/Sweden

Dr. Ryo Jimbo received DDS at Nagasaki University school of Dentistry in 2004. He defended his thesis in 2007 and received PhD. He has received specialist education in Prosthodontics and has also worked in oral & maxillofacial surgery. From 2009, he worked as a visiting researcher at the Department of Biomaterials, Gothenburg University. At present, he works at the Department of Prosthodontics, Malmö University, and is dedicated to implant basic and clinical research, with a special interest in nanotechnology application to implant dentistry.

Dr. Thomas Kofoed, Denmark

Dr. Thomas Kofoed received his dental degree from Aarhus University in 1996. He became specialist in Oral and Maxillofacial Surgery in 2004, from Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. In 2005, he defended his PhD-thesis, at Aarhus University. In 2007 he was appointed Consultant in Oral and Maxillofacial Surgery at Department of Oral and Maxillofacial Surgery, Rigshospitalet, in Copenhagen. Since 2011 appointed as Head of Department at Department of Oral and Maxillofacial Surgery, Rigshospitalet, Copenhagen University Hospital.

Dr. Ulf Lekholm, Sweden

Dr. Ulf Lekholm received his dental degree at Lund University, Dental faculty in Malmö in 1968. He became Doctor of Odontology in 1976 and specialist in Oral maxillofacial surgery in 1977 at the Dental faculty of Gothenburg University. He was appointed the first chairman of the Brånemark Clinic, Gothenburg (1985-2000), and he was appointed professor in Oral implant surgery at the University of Gothenburg in 1988. At present he is professor emeritus.

Dr. Stefan Lundgren, Sweden

Dr. Stefan Lundgren earned his degree in dentistry from the University of Umeå in 1977 and a Ph.D. in 1985. After his Oral and Maxillofacial Surgery Board certification in 1988, he became a Surgical Fellow at the UCLA Medical Center between 1989-90. In 1994, he became the Professor and Acting Chairman of the Department of Oral and Maxillofacial Surgery at the University of Umeå. In 1999, he became its Professor and Chairman. Under Dr. Lundgren’s tutelage, an international group researching the reconstruction of hard and soft tissue during implant surgery published more than 40 original articles, reviews and book chapters over the last 10 years.

Dr. Margareta Molin Thorén, Sweden

Dr. Margareta Molin-Thorén received her dental degree at Faculty of Odontology, Umeå University, 1978. She became specialist in Prosthetic dentistry in 1986, Doctor of Odontology in 1990 at the Dental Faculty of Umeå University. She was appointed professor in Prosthodontics at Umeå University in 1998 and professor in Dental Material Science, Malmö University in 2005. At present she is professor in Prosthodontics and head of the Department of Odontology, Umeå University.

Dr. Stefan Renvert, Sweden

Stefan Renvert is Professor of Oral Health Sciences and Research Director at Kristianstad University, Sweden. He also holds a position as visiting professor at Dublin Dental Hospital, Ireland and at the Blekinge Institute of Technology, Sweden. Professor Renvert is past chairman the Swedish Society of Periodontology and past chairman of the EFP. Professor Renvert at present holds the position as General Secretary of the EFP. Professor Renvert has published over 150 papers in international and national journals. At present Professor Renvert´s research focuses on diagnosis and treatment of peri-implantitis, risk assessments and the association of periodontal disease to cardiovascular disease.

Dr. Eirik Aasland Salvesen, Norway

Dr Eirik Aasland Salvesen is a specialist in Periodontology. He is a partner at TSMG Madlagården in Stavanger (Norway), where he holds the positions as Director of the TSMG Academy. Since 2004 he has been cooperating with Nobel Biocare as a lecturer and in the Mentorship program. Since 2008 he has worked as Clinical consultant for Nobel Biocare in the Nordic countries.

Dr. Massimo Simion, Italy

Degree of Medicine and Surgery at the University of Milan in 1979. Specialization in Odontostomatology and Dental Prosthodontics at the University of Milan in 1982. Professor at the Department of Periodontology at the Dental School of the University of Milan. Member of the Board of EAO 1998 - 2005 and president of EAO 2001-2003 and Immediate Past-President 2004/2005. Founder of the Italian Society of Osseontegration. Active Member and Vice-President of the Italian Society of Periodontology 2003-2005. Referee of several scientific journals.He published several scientific papers and is international lecturer about the topic Periodontology, Osseointegration and Bone Regeneration.

CDT Åsa Möller Sjöholm, Sweden

Åsa Sjöholm received her dental technician degree 1993. She has run her own dental lab, specializing in producing high quality aesthetic products and solutions, since 1995. Production is always in close collaboration with the clinics. She is a member of SAED and Nordic Esthetic Group.

Dr. Kjell Størksen, Norway

Kjell Størksen received his dental education at the University of Bergen in 1979. He has extensive experience with prosthetic tooth replacement and has worked with implant prosthetics since 1990. In addition to regular prosthetic replace¬ments, he has worked extensively with groups of patients with congenital and acquired defects that require special prosthetic solutions. Størksen has been responsible for oral and maxillofacial prosthetics at the Oral and Maxillofacial Surgery, Haukeland University Hospital since 1988. Well-known and highly regarded lecturer in national and international topics such as prosthetics, focusing on implant treatment.

Dr. Eric van Dooren, Belgium

Dr. Van Dooren attended the Katholieke Universiteit Leuven, Belgium, where he received his dentistry degree in 1982. After graduating, he opened a private practice in Antwerp, Belgium, which is limited to periodontics, fixed prosthodontics, and implants. Currently, Dr. Van Dooren is an active member of the European Academy of Esthetic Dentistry. In addition, he is a member of the editorial staff of Teamwork (Germany) and a member of the Belgian Dental Society. Dr. Van Dooren lectures nationally and internationally, mainly on aesthetics, implants and aesthetic periodontal surgery. He has published several articles in international journals and is co-author of The Art of Smile.

Dr. Ann Wennerberg, Sweden

Dr. Ann Wennerberg received her dental degree at the Dental Faculty, Gothenburg University, in 1979. She became Doctor of Medicin in 1996 at the department of Handicap Research and specialist in Oral Prosthodontic in 1997 at the Dental faculty of Gothenburg University. In 2002 she became Professor and in 2003 was appointed chairman of the prosthetic department in Gothenburg. At present she held a position as Professor and chairman at the department of Prosthodontic, Malmö University.

Dr. Nicole Winitsky, Sweden

Nicole Winitsky received her dental degree at the Karolinska Institute, Stockholm in 1997. She specializes in prosthetics and divides her time between the Department of Prosthodontics at St. Erik‘s Hospital and juvenile Prosthodontics at the Eastman Institute. She is a member of the Nordic Esthetic Group.

Dr. George Zarb, Canada

George Zarb spent the last five decades practicing Prosthodontics and pursuing clinical scholarship at the University of Toronto. He has been recognized nationally and internationally and continues to serve his profession as the Editor-in-Chief of the International Journal of Prosthodontics. His many distinctions include his country’s highest civilian award, the Order of Canada.

Dr. Pär Olov Östman, Sweden

Dr Östman received his dental degree from the University of Umeå, Sweden. At present, he runs a private practice full-time. He is also associate professor at Department of Biomaterials, Institute for Surgical Sciences, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden. He has published several scientific articles both in oral pathology and implantology. He has lectured extensively in implant dentistry during the last 10 years. Main focus today is oral handicap, immediate function and R&D.

Parallel Program Speakers

Berit Adielson, Sweden

Graduation from the Specialist Clinic of Periodontology, Örebro Sweden, as a Certified Dental Hygienist in 1975. Worked two years in a private office Started in The University of Gothenburg Specialist Clinic for Periodontology between 1977 until 1987, treated patients and was involved in the Dental Hygienist training. Since 1987 I work at Nobel Biocare with different assignments in the training and education area. Current position: Global Speaker Relationship Management

Dr. Rodrigo Castillo

After completing his studies in continuing education about Restorative implant dentistry at the University of Toronto and a postgraduate program in Esthetic Dentistry at The State University of New York at Buffalo, he focused his private practice in oral rehabilitation in Murcia (Spain). Dr. Castillo is an affiliate member of the prestigious European Academy of Esthetic Dentistry. He has also a Master degree in Implantology at UCLA with Dr Sascha Jovanovic. Dr Castillo is a lecturer up to national and international level in Dental Implants, Dental Photography and Interdisciplinary Dentistry. He has published numerous articles in relevant dental journals.

Gunilla Koch, Sweden

Graduation from University of Gothenburg, Sweden, as a Certified Dental Hygienist in 1983, has worked in public dental health care since 1984. From 1991 working at the Specialist Clinic for Periodontology, Gothenburg, Sweden, and is specialized in treatment of peri-implant lesions and periodon¬titis. Participates in several research projects and studies. Instructor in the Postgraduate program for the postgraduate students in clinical treatment and pre-clinic instruction. Involved in yearly courses for Japanese dental hygienists, since 1995, and the last years also for Italian and German dental hygienists. Has lectured at the SIO Rome International Congress, and at the 6th World Dental Meeting in Japan.

Karin Sjögren, Sweden

Karin Sjögren, PhD, DDS, LDS, diploma in marketing communications, trainer of motivational interviewing, member of MINT (Motivational Interviewing Network of Trainers). Occupation: lecturer in communication in health care and producer of health promotion films (Hälsofrämjande film i Göteborg).

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